Group "International Analytical Laboratory" together with the company "Brooker"

Description

Main activities:

NMR spectroscopy in solutions and solid samples
NMR spectroscopy in non-standard media (ionic liquids, colloidal systems)
Conducting workshops on practical NMR spectroscopy
The tasks of determining the structure of molecules, determining the purity of a substance, monitoring reactions are fundamental in organic synthesis, the study of natural compounds, in organoelemental chemistry.

Over the past 35 years, nuclear magnetic resonance has developed into a powerful analytical tool for solving problems in various fields of science. Improving the hardware base, introducing new materials and computational methods significantly expanded the possibilities of NMR spectroscopy, making available techniques that seemed difficult or expensive.

The advantages of NMR spectroscopy:

· No destructive effect on the sample

· Qualitative and quantitative analysis of directly reactive mixtures

· Unique structural information

· Easy sample preparation

· Applicability to organic and organometallic molecules and systems

Our group performs molecular structure studies using modern physicochemical methods, among which a significant role is played by nuclear magnetic spectroscopy
resonance (NMR). The method allows literally collecting an unknown molecule from atoms using spectral data. We use the most advanced NMR spectrometers that
allow to investigate the substance by traditional high-resolution NMR methods, as well as by rapidly developing solid, diffusion and microtomography techniques.
At present, six Brooker NMR spectrometers operate at the Institute of Organic Chemistry, RAS: two at 200 MHz, at 300, 400, 500 and 600 MHz, which are necessary tools for
perform various studies.

Modern methods of NMR spectroscopy, including two-dimensional ones, are widely used for complex molecules. The main devices for solving such problems are at 500 and 600 MHz.
In addition to establishing the structure of molecules, NMR spectroscopy is used to study the kinetics of chemical reactions and to study their mechanisms, for more detailed
studying molecules, including calculating the energy of various conformations, rotation barriers, inversions, etc.

Another application of NMR directly related to the subject of the institute is the solution of problems associated with catalysis and mechanisms of catalytic reactions. NMR solid samples
allows you to study catalysts.

NMR spectroscopy at the Institute of Organic Chemistry of the Russian Academy of Sciences is necessary for an institute method of research, the use of various one- and two-dimensional techniques on protons and heterojunnels of other
makes it applicable for a very wide range of tasks.